The Echo Maker by Richard Powers

Set in Nebraska along the Platte River, this award-winning novel is a masterful, lyrical weave of cranes and brains, consciousness and memory, science and love, fame and forgetting. It's the story of Mark, a young man who survives a serious, mysterious accident, but with a brain injury that makes him believe that his sister, Karin, is an imposter. She appeals to a famous neurologist, Gerald Weber, who agrees to consult in order to see the rare syndrome for himself. The author brings to vivid life these three characters and a motley crew of Mark's friends and caretakers. The pages of this book are dense with the marvels of human brain science, the plasticity and tyranny of the mind, and the ways we humans perceive ourselves and each other. One mystery gets solved as a dozen more are revealed. Love it or not, you won't regret reading this book.